Popular weight-loss and diabetes medications like Ozempic and Wegovy may also help curb alcohol consumption, according to a new study presented at the European Congress on Obesity. Researchers found that GLP-1 medications helped heavy drinkers reduce their alcohol intake by nearly 70%—more than what’s typically achieved with nalmefene, a drug specifically approved to treat alcohol dependence in Europe.
The study followed 262 adults prescribed GLP-1 drugs such as semaglutide or liraglutide for weight loss. Those who drank heavily—defined as more than six standard drinks per week—saw the most dramatic declines, without any reported increase in drinking. Participants also lost an average of 17 pounds over four months.
Experts believe the medications may influence brain pathways tied to reward and cravings, potentially dulling the pleasure associated with alcohol. “This gives people a degree of control that’s unique,” said study author Dr. Maurice O’Farrell of the Medication Weight Loss Clinic in Dublin.
While the real-world study lacked a control group and relied on self-reported data, researchers say the findings are promising and warrant further research. If validated, GLP-1 medications could offer a new option for people struggling with alcohol use who haven’t responded to traditional treatments.